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dc.contributor.authorIto, E.
dc.contributor.authorSatake, M.
dc.contributor.authorOfuji, K.
dc.contributor.authorMcMahon, T.
dc.contributor.authorSilke, J.
dc.contributor.authorJames, K.
dc.contributor.authorYasumoto, T.
dc.date.accessioned2017-03-31T11:42:24Z
dc.date.available2017-03-31T11:42:24Z
dc.date.issued2001
dc.identifier.citationIto, E., Satake, M., Ofuji, K., McMahon, T., Silke, J., James, K., Yasumoto, T. (2001). Small intestinal injuries in mice caused by a new toxin, Azaspiracid, isolated from Irish mussels, in: Harmful Algal Blooms 2000, Hallegraeff, G., et al. (Eds), Intergovernmental Oceanographic Commission of UNESCO 2001, pp. 395-398, http://unesdoc.unesco.org/images/0012/001266/126659eo.pdfen_GB
dc.identifier.urihttp://hdl.handle.net/10793/1268
dc.description.abstractPathological changes of the small intestine caused by a new toxin, azaspiracid, from Irish mussels were studied. Human poisoning cases included both diarrhetic shellfish and paralitic shellfish poisoning symptoms. The present paper focused on the former. Injuries were observed in the Upper part of the small intestine, where lamina propria in the villi became atrophied at the initial stage, followed by desquamation of epithelial cells and shortening of villi. The injuries were different from the DSP toxin okadaic acid; 1) they developed very slowly after a lag time of about 3 hr, 2) recovery was very late, 3) initial target and process were different.en_GB
dc.language.isoenen_GB
dc.publisherUNESCOen_GB
dc.subjectAzaspiraciden_GB
dc.subjectMusselsen_GB
dc.titleSmall intestinal injuries in mice caused by a new toxin, Azaspiracid, isolated from Irish musselsen_GB
dc.typeBook chapteren_GB
refterms.dateFOA2018-01-12T05:51:21Z


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