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Please use this identifier to cite or link to this item: http://hdl.handle.net/10793/977

Title: Balancing selection on MHC class I in wild brown trout Salmo trutta
Authors: O'Farrell, B
Dennis, C
Benzie, JA
McGinnity, P
Carlsson, J
De Eyto, E
Coughlan, J
Igoe, F
Meehan, R
Cross, T
Keywords: Major Histocompatibility complex
variation
fish
genetic diversity
isolated populations
Issue Date: Sep-2012
Publisher: Wiley
Citation: O’Farrell, B., Dennis, C., Benzie, J. A., McGinnity, P., Carlsson, J., de Eyto, E., Coughlan, J. P., Igoe, F., Meehan, R. and Cross, T. F. (2012), Balancing selection on MHC class I in wild brown trout Salmo trutta. Journal of Fish Biology, 81: 1357–1374. doi: 10.1111/j.1095-8649.2012.03421.x
Series/Report no.: Journal of Fish Biology;Vol 81. Issue 4.
Abstract: Evidence is reported for balancing selection acting on variation at major histocompatibility complex (MHC) in wild populations of brown trout Salmo trutta. First, variation at an MHC class I (satr-uba)–linked microsatellite locus (mhc1) is retained in small S. trutta populations isolated above waterfalls although variation is lost at neutral microsatellite markers. Second, populations across several catchments are less differentiated at mhc1 than at neutral markers, as predicted by theory. The population structure of these fish was also elucidated.
URI: http://hdl.handle.net/10793/977
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