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Title: AZASPIRACIDS – Toxicological Evaluation, Test Methods and Identifcation of the Source Organisms (ASTOX II)
Authors: Kilcoyne, Jane
Jauffrais, Thierry
Twiner, Michael J.
Doucette, Gregory J.
Aasen Bunes, John A.
Sosa, Silvio
Krock, Bernd
Séhet, Véronique
Nulty, Ciara
Salas, Rafael
Clarke, Dave
Geraghty, Jennifer
Duffy, Conor
Foley, Barry
John, Uwe
Quilliam, Michael A.
McCarron, Pearse
Miles, Christopher O.
Silke, Joe
Cembella, Allan
Tillmann, Urban
Hess, Philipp
Keywords: ASTOX 2
marine biotoxins
shellfish poisoning
certified reference materials
Issue Date: 2014
Publisher: Marine Institute
Series/Report no.: Marine Research Sub-Programme (NDP 2007-2013) Series;
Abstract: Since the Irish monitoring program was set up in 2001 azaspiracids (AZAs) have been detected in shellfish above the regulatory limit every year with the exception of 2004. The south west coast of Ireland is especially prone to the onsets of AZA events. Over this period a number of poisoning incidents associated with this toxin group have occurred, all related to Irish shellfish. In 2003 the Marine Institute was awarded funding for a research project named ASTOX. This project was very successful in producing a range of reference materials (RMs, which are essential for accurate detection and monitoring, and which up to this point were unavailable. The project also examined the toxicity of AZAs, primarily using in vitro cell assays but some in vivo studies were also performed. The overall aims of the ASTOX 2 project were to strengthen knowledge on the causative organism and toxicity of AZAs. The project aims were grouped into three areas: ecology, chemical support and toxicology.
ISSN: 2009-3195
Appears in Collections:Marine Research Sub-Programme (NDP 2007-2013) Series

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