Peer Reviewed Scientific Papers
http://hdl.handle.net/10793/49
2024-02-11T16:55:12Z
2024-02-11T16:55:12Z
Structure Elucidation, Relative LC–MS Response and In Vitro Toxicity of Azaspiracids Isolated from Mussels (Mytilus edulis)
Kilcoyne, Jane
Twiner, Michael J.
McCarron, Pearse
Crain, Sheila
Giddings, Sabrina D.
Foley, Barry
Rise, Frode
Hess, Philipp
Wilkins, Alistair L.
Miles, Christopher O.
http://hdl.handle.net/10793/1823
2023-03-21T02:04:43Z
2015-01-01T00:00:00Z
Structure Elucidation, Relative LC–MS Response and In Vitro Toxicity of Azaspiracids Isolated from Mussels (Mytilus edulis)
Kilcoyne, Jane; Twiner, Michael J.; McCarron, Pearse; Crain, Sheila; Giddings, Sabrina D.; Foley, Barry; Rise, Frode; Hess, Philipp; Wilkins, Alistair L.; Miles, Christopher O.
Azaspiracids (AZAs) are marine biotoxins produced by dinoflagellates that can accumulate in shellfish, which if consumed can lead to poisoning events. AZA7–10, 7–10, were isolated from shellfish and their structures, previously proposed on the basis of only LC–MS/MS data, were confirmed by NMR spectroscopy. Purified AZA4–6, 4–6, and 7–10 were accurately quantitated by qNMR and used to assay cytotoxicity with Jurkat T lymphocyte cells for the first time. LC–MS(MS) molar response studies performed using isocratic and gradient elution in both selected ion monitoring and selected reaction monitoring modes showed that responses for the analogues ranged from 0.3 to 1.2 relative to AZA1, 1. All AZA analogues tested were cytotoxic to Jurkat T lymphocyte cells in a time- and concentration-dependent manner; however, there were distinct differences in their EC50 values, with the potencies for each analogue being: AZA6 > AZA8 > AZA1 > AZA4 ≈ AZA9 > AZA5 ≈ AZA10. This data contributes to the understanding of the structure–activity relationships of AZAs.
Peer reviewed.
J. Agric. Food Chem. 2015, 63, 20, 5083–5091
Publication Date:April 24, 2015
https://doi.org/10.1021/acs.jafc.5b01320
Copyright © 2015 American Chemical Society
2015-01-01T00:00:00Z
Towards vibrant fish populations and sustainable fisheries that benefit all: learning from the last 30 years to inform the next 30 years
Cooke, Steven J.
Fulton, Elizabeth A.
Sauer, Warwick H. H.
Lynch, Abigail J.
Link, Jason S.
Koning, Aaron A.
Jena, Joykrushna
Silva, Luiz G. M.
King, Alison J.
Kelly, Rachel
Osborne, Matthew
Nakamura, Julia
Preece, Ann L.
Hagiwara, Atsushi
Forsberg, Kerstin
Kellner, Julie B.
Coscia, Ilaria
Helyar, Sarah
Barange, Manuel
Nyboer, Elizabeth
Williams, Meryl J.
Chuenpagdee, Ratana
Begg, Gavin A.
Gillanders, Bronwyn M.
http://hdl.handle.net/10793/1820
2023-03-21T02:04:58Z
2023-01-01T00:00:00Z
Towards vibrant fish populations and sustainable fisheries that benefit all: learning from the last 30 years to inform the next 30 years
Cooke, Steven J.; Fulton, Elizabeth A.; Sauer, Warwick H. H.; Lynch, Abigail J.; Link, Jason S.; Koning, Aaron A.; Jena, Joykrushna; Silva, Luiz G. M.; King, Alison J.; Kelly, Rachel; Osborne, Matthew; Nakamura, Julia; Preece, Ann L.; Hagiwara, Atsushi; Forsberg, Kerstin; Kellner, Julie B.; Coscia, Ilaria; Helyar, Sarah; Barange, Manuel; Nyboer, Elizabeth; Williams, Meryl J.; Chuenpagdee, Ratana; Begg, Gavin A.; Gillanders, Bronwyn M.
A common goal among fisheries science professionals, stakeholders, and rights holders is to ensure the persistence and resilience of vibrant fish populations and sustainable, equitable fisheries in diverse aquatic ecosystems, from small headwater streams to offshore pelagic waters. Achieving this goal requires a complex intersection of science and management, and a recognition of the interconnections among people, place, and fish that govern these tightly coupled socioecological and sociotechnical systems. The World Fisheries Congress (WFC) convenes every four years and provides a unique global forum to debate and discuss threats, issues, and opportunities facing fish populations and fisheries. The 2021 WFC meeting, hosted remotely in Adelaide, Australia, marked the 30th year since the first meeting was held in Athens, Greece, and provided an opportunity to reflect on progress made in the past 30 years and provide guidance for the future. We assembled a diverse team of individuals involved with the Adelaide WFC and reflected on the major challenges that faced fish and fisheries over the past 30 years, discussed progress toward overcoming those challenges, and then used themes that emerged during the Congress to identify issues and opportunities to improve sustainability in the world's fisheries for the next 30 years. Key future needs and opportunities identified include: rethinking fisheries management systems and modelling approaches, modernizing and integrating assessment and information systems, being responsive and flexible in addressing persistent and emerging threats to fish and fisheries, mainstreaming the human dimension of fisheries, rethinking governance, policy and compliance, and achieving equity and inclusion in fisheries. We also identified a number of cross-cutting themes including better understanding the role of fish as nutrition in a hungry world, adapting to climate change, embracing transdisciplinarity, respecting Indigenous knowledge systems, thinking ahead with foresight science, and working together across scales. By reflecting on the past and thinking about the future, we aim to provide guidance for achieving our mutual goal of sustaining vibrant fish populations and sustainable fisheries that benefit all. We hope that this prospective thinking can serve as a guide to (i) assess progress towards achieving this lofty goal and (ii) refine our path with input from new and emerging voices and approaches in fisheries science, management, and stewardship.
Our team of authors was drawn from the International Program Committee and plenary speakers from the 2021 WFC, as well as several early-career scholars. In sum, the 24 authors reside in 12 countries that span all continents (except Antarctica), with roughly equal gender balance, and are drawn from academia, industry, government (at various levels from regional to the Food and Agriculture Organization of the United Nations—FAO), and the nongovernmental sector. We acknowledge that our authorship team does not represent all perspectives, and that some voices, in particular Indigenous cultural perspectives, are not represented here. We recognize this as a major deficiency to this opinion piece, but have taken this as an opportunity to improve our perspectives. This paper is timely and given the diverse perspectives of authors (informed by participation in the WFC) we feel that these ideas are worth sharing with the broader fisheries science and management community..
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
Original link: Cooke, S.J., Fulton, E.A., Sauer, W.H.H. et al. Towards vibrant fish populations and sustainable fisheries that benefit all: learning from the last 30 years to inform the next 30 years. Rev Fish Biol Fisheries (2023). https://doi.org/10.1007/s11160-023-09765-8
Peer Reviewed
2023-01-01T00:00:00Z
Population structure and connectivity in the genus Molva in the Northeast Atlantic
McGill, L
McDevitt, A D
Hellemans, B
Neat, F
Knutsen, H
Mariani, S
Christiansen, H
Johansen, T
Volckaert, F A M
Coscia, I
http://hdl.handle.net/10793/1818
2023-03-21T02:04:50Z
2023-01-01T00:00:00Z
Population structure and connectivity in the genus Molva in the Northeast Atlantic
McGill, L; McDevitt, A D; Hellemans, B; Neat, F; Knutsen, H; Mariani, S; Christiansen, H; Johansen, T; Volckaert, F A M; Coscia, I
In fisheries, operational management units and biological data often do not coincide. In many cases, this is not even known due to the lack of information about a species’ population structure or behaviour. This study focuses on two such species, the common ling Molva molva and the blue ling M. dypterygia, two Northeast Atlantic gadoids with overlapping geographical distribution, but different depth habitats. Heavily exploited throughout their ranges, with declining catches, little is known about their population structure. Genotyping-by-sequencing at thousands of genetic markers indicated that both species are separated into two major groups, one represented by samples from the coasts of western Scotland, Greenland, and the Bay of Biscay and the other off the coast of Norway. This signal is stronger for the deeper dwelling blue ling, even though adult dispersal was also identified for this species. Despite small sample sizes, fine-scale patterns of genetic structure were identified along Norway for common ling. Signatures of adaptation in blue ling consisted in signs of selections in genes involved in vision, growth, and adaptation to cold temperatures.
Peer reviewed
2023-01-01T00:00:00Z
Lessons from a Marine Spatial Planning data management process for Ireland
Flynn, Sarah
Meaney, Will
Leadbetter, Adam M.
Fisher, Jeffrey P.
Nic Aonghusa, Caitriona
http://hdl.handle.net/10793/1603
2021-02-04T10:41:13Z
2020-01-01T00:00:00Z
Lessons from a Marine Spatial Planning data management process for Ireland
Flynn, Sarah; Meaney, Will; Leadbetter, Adam M.; Fisher, Jeffrey P.; Nic Aonghusa, Caitriona
This paper presents a framework containing ten components to deliver a
data management process for the storage and management of data used
for Marine Spatial Planning (MSP) in Ireland. The work includes a data
process flow and a recommended solution architecture. The architecture
includes a central data catalogue and a spatial storage system. The
components of the process are presented to maximise the reuse
potential of any dataset within an MSP context. The terms ‘Suitability’
and ‘Readiness’ in the MSP context are offered as both formal and
considered assessments of data, as is the applicability of a data
stewardship maturity matrix. How data contained in such a storage
system can be published externally to potential consumers of these
data is also explored. The process presents a means of managing data
and metadata to ensure data lineage is optimised by carrying
information about the origin of and the processing applied to the data;
to evaluate the quality and relevance of geospatial datasets for use in
MSP decisions in Ireland. The process was piloted in the National
Marine Planning Framework for Ireland in the development of draft
map products; feedback from the public consultation is ongoing and
not presented.
Peer-reviewed
2020-01-01T00:00:00Z